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Nicotinamide Riboside

Nicotinamide Riboside

Nicotinamide Riboside: Energize and Boost Your Mood With This Supplement

Nicotinamide riboside (NR) is a unique form of vitamin B3 and a precursor to nicotinamide adenine dinucleotide (NAD+), which is essential for mitochondrial energy production.

It has been shown that nicotinamide riboside supplementation can increase NAD+ levels in the body by about 50% after eight weeks, improving energy levels and resilience to stress.1, 2, 3

What are the benefits of NR intake?

There are variations in how NAD+ precursors like NR can benefit health. For example, research has indicated that NR supplementation can help protect against high-fat diet-induced obesity and enhance oxidative metabolism.4, 5

How to properly include NR supplements into your diet?

Nicotinamide riboside could be considered by individuals interested in supporting their energy metabolism, particularly those experiencing age-related declines in NAD+ or conditions linked to mitochondrial dysfunction. The usual dosage, as suggested by some studies, is two capsules of 150 mg, although other studies used higher amounts.1

However, there are precautions to consider. Despite nicotinamide riboside being well-tolerated in clinical trials and showing beneficial effects on NAD+ levels, further research is required to understand its long-term safety and effectiveness.2

Let’s sum up

In summary, nicotinamide riboside is a vitamin B3 derivative that serves as a precursor to NAD+, playing a crucial role in maintaining cellular energy and potentially helping mitigate some effects of aging. While promising, recommendations for NR supplementation should be made cautiously, and future research will likely continue to reveal its breadth of benefits and optimal applications in health maintenance and disease prevention.


  • 1) Mitochondrial Dysfunction  
    A Functional Medicine Approach to Diagnosis and Treatment: Get Rid of Fat, Fatigue, and Brain Fog
    Book | 2019 | Michael T. Chang

  • 2) Eat for Energy  
    How to beat fatigue, supercharge your mitochondria, and unlock all-day energy
    Book | 2022 | Ari Whitten, Alex Leaf, M.S.

  • 3) Defy Aging  
    A beginner's guide to the new science of longer life and better health
    Book | 2021 | Beth Bennett

  • 4) Mitochondria and the Future of Medicine  
    The Key to Understanding Disease, Chronic Illness, Aging, and Life Itself
    Book | 2018 | Dr. Lee Know

  • 5) Cheating Death  
    The new science of living longer and better
    Book | 2023 | Dr. Rand McClain

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